Clint At LLNL

Clinton is a Pathogen Bioinformatics software engineer in the Computing and Applications Research division at LLNL. Clinton was a summer student at the Lab from 2000-2002. He recieved his B.S. in Computer Science and Engineering from Northern Arizona University in 2002, which is when he came to work full-time in the Biodefense Informatics group.

Clinton is the lead architect of the KPATH pathogen signature design system. KPATH is used to provide genomic analysis and DNA detection signatures for pathogens including SARS, Bird-Flu, and Foot-and-Mouth Disease, supporting collaborators such as the Centers for Disease Control and Prevention, and the US Department of Agriculture. Clinton also contributed to the AS2TS threading-based protein modeler, and worked on a set of tools that perform structural comparisons of groups of proteins.

Press Releases

New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed (2007)

Characterizing Virulent Pathogens - Multiplexed assays and proteomics research are helping the nation counter potential biothreats (2007)

Diagnosing Flu Fast - A new Livermore tool can quickly tell which patients have influenza or another respiratory virus (2006)

Protecting the Nation's Livestock - A Livermore developed assay rapidly detects foot-and-mouth disease and look-alike livestock diseases (2006)

Landmark Work on SARS Signatures (2006)

Finding genetic fingerprints of disease-causing microbes (2006)

On the Front Lines of Biodefense - A Livermore team is developing DNA-based signatures to quickly and accurately identify pathogens (2004)

BASIS Counters Airborne Bioterrorism (2003)

Although Challenges Remain 'Unprecedented' Progess Made in Countering Biological, Chemical Terrorism (2003)

Lawrence Livermore Research Team Finds Unique DNA Signatures to Improve Anthrax Detection (2002)

Advances Developed To Detect Bioterrorist Agents Could Find Use In Protecting Food Supplies (2002)

Lab DNA signature tools used to detect naturally occurring food pathogens (2002)

Lab work speeds plague detection (2001)

Uncovering Bioterrorism - DNA-based signatures are needed to quickly and accurately identify biological warfare agents and their makers (2000)

Publications

Gardner, S. N., M. W. Lam, T. Kuczmarski, J. R. Smith, C. L. Torres, and T. R. Slezak (2005), "Draft versus finished sequence data for DNA and protein diagnostic signature development," Nucleic Acids Research, 33(18):5838-5850.

Zemla, A., C. E. Zhou, T. Slezak, T. Kuczmarski, D. Rama, C. Torres, D. Sawicka, D. Barsky (2005), "AS2TS system for protein structure modeling and analysis" Nucleic Acids Research 33(Web-Server-Issue): 111-115 (2005)

Gardner, S. N., M. Lam, N. Mulakken, C. Torres, J. Smith, and T. Slezak (2004), "Sequencing needs for viral diagnostics," Journal of Clinical Microbiology, 42:5472-5476.

Slezak, T., T. Kuczmarski, L. Ott, C. Torres, D. Medeiros, J. Smith, B. Truitt, N. Mulakken, M. Lam, E. Vitalis, A. Zemla, C. E. Zhou, and S. N. Gardner (2003), "Comparative genomics tools applied to bioterrorism defense," Briefings in Bioinformatics, 4(2):133-149.